Selected Publications

Bexell, D, Gunnarsson, S, Tormin, A, Darabi, A, Gisselsson, D, Roybon, L, Scheding, S, and Bengzon, J (2009).
Bone marrow multipotent mesenchymal stroma cells act as pericyte-like migratory vehicles in experimental gliomas.
Mol Ther 17(1):183-90.

Strate, I, Min, TH, Iliev, D, and Pera, EM (2009).
Retinol dehydrogenase 10 is a feedback regulator of retinoic acid signalling during axis formation and patterning of the central nervous system.
Development 136(3):461-72.

Li, JY, Englund, E, Holton, JL, Soulet, D, Hagell, P, Lees, AJ, Lashley, T, Quinn, NP, Rehncrona, S, Bjorklund, A, Widner, H, Revesz, T, Lindvall, O, and Brundin, P (2008).
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation.
Nat Med.

Nygren, JM, Liuba, K, Breitbach, M, Stott, S, Thoren, L, Roell, W, Geisen, C, Sasse, P, Kirik, D, Bjorklund, A, Nerlov, C, Fleischmann, BK, Jovinge, S, and Jacobsen, SEW (2008).
Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.
Nat Cell Biol 10(5):584-92.

Anderson, K, Rusterholz, C, Mansson, R, Jensen, CT, Bacos, K, Zandi, S, Sasaki, Y, Nerlov, C, Sigvardsson, M, and Jacobsen, SE (2007).
Ectopic expression of PAX5 promotes self renewal of bi-phenotypic myeloid progenitors co-expressing myeloid and B-cell lineage associated genes.
Blood.

Bexell, D, Gunnarsson, S, Nordquist, J, and Bengzon, J (2007).
Characterization of the subventricular zone neurogenic response to rat malignant brain tumors.
Neuroscience 147(3):824-32.

Hou, S, Maccarana, M, Min, TH, Strate, I, and Pera, EM (2007).
The Secreted Serine Protease xHtrA1 Stimulates Long-Range FGF Signaling in the Early Xenopus Embryo.
Dev Cell 13(2):226-241.

Rossi, DJ, Bryder, D, Seita, J, Nussenzweig, A, Hoeijmakers, J, and Weissman, IL (2007).
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age.
Nature 447(7145):725-9.

Buza-Vidas, N, Antonchuk, J, Qian, H, Mansson, R, Luc, S, Zandi, S, Anderson, K, Takaki, S, Nygren, JM, Jensen, CT, and Jacobsen, SEW (2006).
Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK.
Genes Dev 20(15):2018-23.

Hernebring, M, Brolen, G, Aguilaniu, H, Semb, H, and Nystrom, T (2006).
Elimination of damaged proteins during differentiation of embryonic stem cells.
Proc Natl Acad Sci U S A 103(20):7700-5.

Jakubs, K, Nanobashvili, A, Bonde, S, Ekdahl, CT, Kokaia, Z, Kokaia, M, and Lindvall, O (2006).
Environment matters: synaptic properties of neurons born in the epileptic adult brain develop to reduce excitability.
Neuron 52(6):1047-59.

Kirstetter, P, Anderson, K, Porse, BT, Jacobsen, SE, and Nerlov, C (2006).
Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.
Nat Immunol.

Lindvall, O and Kokaia, Z (2006).
Stem cells for the treatment of neurological disorders
Nature 441:1094-1096.

Xian, X, Hakansson, J, Stahlberg, A, Lindblom, P, Betsholtz, C, Gerhardt, H, and Semb, H (2006).
Pericytes limit tumor cell metastasis.
J Clin Invest 116(3):642-651.

Adolfsson, J, Mansson, R, Buza-Vidas, N, Hultquist, A, Liuba, K, Jensen, CT, Bryder, D, Yang, L, Borge, O, Thoren, LA, Anderson, K, Sitnicka, E, Sasaki, Y, Sigvardsson, M, and Jacobsen, SE (2005).
Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.
Cell 121(2):295-306.

Cacci, E, Claasen, J, and Kokaia, Z (2005).
Microglia-derived tumor necrosis factor-alpha exaggerates death of newborn hippocampal progenitor cells in vitro.
J Neurosci Res 80(6):789-97.

Castor, A, Nilsson, L, Astrand-Grundstrom, I, Buitenhuis, M, Ramirez, C, Anderson, K, Strombeck, B, Garwicz, S, Bekassy, AN, Schmiegelow, K, Lausen, B, Hokland, P, Lehmann, S, Juliusson, G, Johansson, B, and Jacobsen, SE (2005).
Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia.
Nat Med 11(6):630-7.

Castor, A, Nilsson, L, Astrand-Grundstrom, I, Buitenhuis, M, Ramirez, C, Anderson, K, Strombeck, B, Garwicz, S, Bekassy, AN, Schmiegelow, K, Lausen, B, Hokland, P, Lehmann, S, Juliusson, G, Johansson, B, and Jacobsen, SEW (2005).
Distinct patterns of hematopoietic stem cell involvement in acute lymphoblastic leukemia.
Nat Med 11(6):630-7.

Collin, T, Arvidsson, A, Kokaia, Z, and Lindvall, O (2005).
Quantitative analysis of the generation of different striatal neuronal subtypes in the adult brain following excitotoxic injury.
Exp Neurol 195(1):71-80.

Larsson, J, Blank, U, Klintman, J, Magnusson, M, and Karlsson, S (2005).
Quiescence of hematopoietic stem cells and maintenance of the stem cell pool is not dependent on TGF-beta signaling in vivo.
Exp Hematol 33(5):592-6.

Thompson, L, Barraud, P, Andersson, E, Kirik, D, and Bjorklund, A (2005).
Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections.
J Neurosci 25(27):6467-77.

Lindvall, O, Kokaia, Z, and Martinez-Serrano, A (2004).
Stem cell therapy for human neurodegenerative disorders-how to make it work.
Nat Med 10 Suppl:S42-50.

Nygren, JM, Jovinge, S, Breitbach, M, Sawen, P, Roll, W, Hescheler, J, Taneera, J, Fleischmann, BK, and Jacobsen, SE (2004).
Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation.
Nat Med 10(5):494-501.

Arvidsson, A, Kirik, D, Lundberg, C, Mandel, RJ, Andsberg, G, Kokaia, Z, and Lindvall, O (2003).
Elevated GDNF levels following viral vector-mediated gene transfer can increase neuronal death after stroke in rats.
Neurobiol Dis 14(3):542-56.

Bjornsson, JM, Larsson, N, Brun, AC, Magnusson, M, Andersson, E, Lundstrom, P, Larsson, J, Repetowska, E, Ehinger, M, Humphries, RK, and Karlsson, S (2003).
Reduced proliferative capacity of hematopoietic stem cells deficient in Hoxb3 and Hoxb4.
Mol Cell Biol 23(11):3872-83.